Machine learning has become an indispensable tool to mine chemical information from compound databases
support-vector machine constructs a hyperplane or set of hyperplanes in a high- or infinite-dimensional space.
The prediction of the ensemble is given as the averaged prediction of the individual classifiers.
an optimized distributed gradient boosting library designed to be highly efficient, flexible and portable.
a class of feedforward artificial neural network consisted of at least three layers of nodes.
Priorities for TB research and development include a vaccine to lower the risk of infection, a vaccine or new drug treatment to cut the risk of TB disease in the 1.7 billion people already latently infected, rapid diagnostics for use at the point of care and simpler, shorter drug regimens for treating TB disease.
The recommendation to use bedaquiline as part of longer MDR-TB treatment regimens was conditional upon proper patient selection, a regimen design WHO recommendations.
Clofazimine is a riminophenazine that is used to treat leprosy. Its use in MDR-TB treatment is being explored in preclinical models of TB infection, to better understand its anti-TB effects.