Nav1.9
VGSC-DB Target ID | NAT009 |
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Name | Sodium channel protein type 11 subunit alpha |
Synonyms |
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Description | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization. |
Organism | Human, Mouse, Rat |
PDB ID | None |
UniProt | Q9UI33, Q9R053, O88457 |
Compounds |
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VGSC-DB ID | Sructure | PubChem CID | Molecular Formula | IC50/EC50* (nM) | Binding Site | Organism | Article DOI |
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