Nav1.6

Target Information
VGSC-DB Target ID NAT006
Name Sodium channel protein type 8 subunit alpha
Synonyms
  • Sodium channel protein type VIII subunit alpha
  • Voltage-gated sodium channel subunit alpha Nav1.6
Description Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.
Organism Human, Mouse
PDB ID None
UniProt Q9UQD0, Q9WTU3
Structure
SOURCE IDENTIFIER METHOD RESOLUTION ORGANISMS DOWNLOAD
AlphaFold2 AF-Q9UQD0-F1 Predicted Human
AlphaFold2 AF-Q9WTU3-F1 Predicted Mouse
Compounds
VGSC-DB ID Sructure PubChem CID Molecular Formula IC50/EC50* (nM) Binding Site Organism Article DOI