Nav1.4
VGSC-DB Target ID | NAT004 |
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Name | Sodium channel protein type 4 subunit alpha |
Synonyms |
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Description | Pore-forming subunit of a voltage-gated sodium channel complex through which Na+ ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states.Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K+ levels. |
Organism | Human, Mouse, Rat |
PDB ID | 6AGF |
UniProt | P35499, Q9ER60, P15390 |
Compounds |
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VGSC-DB ID | Sructure | PubChem CID | Molecular Formula | IC50/EC50* (nM) | Binding Site | Organism | Article DOI |
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