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Data

Metrics True Negative False Positive False Negative True Positive Accuracy ROC_AUC F1_Score EF_1%
Value 48 2 0 51 0.98 0.99 0.98 1.98
Hyper-parameter n_estimators learning_rate subsample max_depth gamma min_child_weight colsample_bytree More
Value 273 0.29 1 35 0 1 1
Feature_importance num_heavy… gauss(o=2… gauss(o=2… lat_A lat_OA gauss(o=2… atp4_C_OA More
Value 0.077 0.055 0.048 0.046 0.043 0.038 0.035
n_estimators learning_rate subsample max_depth gamma min_child_weight colsample_bytree colsample_bylevel colsample_bynode reg_alpha reg_lambda
273 0.29 1 35 0 1 1 1 1 0 1
num_heavy_atoms gauss(o=2,_w=0.5,_c=8) gauss(o=2,_w=1.5,_c=8) lat_A lat_OA gauss(o=2,_w=0.9,_c=8) atp4_C_OA gauss(o=2,_w=2,_c=8) gauss(o=1,_w=1.5,_c=8) gauss(o=1.5,_w=0.3,_c=8) gauss(o=1,_w=0.7,_c=8) gauss(o=3,_w=3,_c=8) gauss(o=2,_w=0.7,_c=8) ele_A_C gauss(o=1,_w=0.5,_c=8) lat_N ad4_solvation(d-sigma=3.6,_s/q=0.01097,_c=8) vdw(i=4,_j=8,_s=0,_^=100,_c=8) acceptor_acceptor_quadratic(o=1,_c=8) gauss(o=4,_w=3,_c=8) atp4_C_C gauss(o=2,_w=3,_c=8) ele_A_N gauss(o=1,_w=3,_c=8) vdw(i=6,_j=12,_s=1,_^=100,_c=8) num_tors_sqr ele_A_HD electrostatic(i=2,_^=100,_c=8) gauss(o=3,_w=2,_c=8) gauss(o=1,_w=2,_c=8) num_tors_add ele_HD_HD lat_HD ele_HD_N ele_OA_OA atp4_A_A ele_C_OA electrostatic(i=1,_^=100,_c=8) num_tors_sqrt gauss(o=4,_w=2,_c=8) ele_N_N atp4_A_HD ele_A_OA nn_vina_gauss_2 hydrophobic(g=0.5,_b=1.5,_c=8) ele_C_C ele_A_A gauss(o=0,_w=2,_c=8) lat_C donor_donor_quadratic(o=1,_c=8) acceptor_acceptor_quadratic(o=0.5,_c=8) nn_vina_affinity atp4_A_C siteflex_SIDECHAIN_BETA gauss(o=3,_w=1.5,_c=8) gauss(o=3,_w=0.9,_c=8) gauss(o=0,_w=0.7,_c=8) gauss(o=2,_w=0.3,_c=8) gauss(o=2.5,_w=0.3,_c=8) gauss(o=1,_w=0.3,_c=8) gauss(o=4,_w=1.5,_c=8) gauss(o=0,_w=1.5,_c=8)
0.077 0.055 0.048 0.046 0.043 0.038 0.035 0.033 0.031 0.027 0.026 0.026 0.025 0.022 0.022 0.020 0.020 0.018 0.015 0.015 0.015 0.015 0.014 0.013 0.013 0.013 0.013 0.013 0.013 0.012 0.012 0.012 0.011 0.011 0.011 0.010 0.009 0.009 0.009 0.009 0.008 0.008 0.007 0.007 0.007 0.007 0.007 0.007 0.006 0.006 0.006 0.006 0.005 0.005 0.004 0.004 0.004 0.004 0.003 0.003 0.003 0.003

Figures

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Visualization

No. Ligand Score Complex Site
1 CHEMBL572878_1 1.00
2 CHEMBL1087650 1.00
3 CHEMBL572878 1.00
4 CHEMBL402548 1.00
5 CHEMBL1087650_1 1.00
6 CHEMBL290921 1.00
7 CHEMBL1077317_2 1.00
8 CHEMBL184742 1.00
9 ZINC38899560 1.00
10 CHEMBL1213975_1 1.00
11 CHEMBL1077317_1 1.00
12 CHEMBL402548_1 1.00
13 CHEMBL1213975 1.00
14 CHEMBL1213974 1.00
15 CHEMBL1077317 1.00
16 ZINC10129833 1.00
17 ZINC20860492 1.00
18 CHEMBL1171532 1.00
19 ZINC20503836 1.00
20 CHEMBL122182_1 1.00
21 CHEMBL122182 1.00
22 ZINC05409198 0.99
23 ZINC39940652 0.99
24 CHEMBL169390 0.99
25 ZINC08790510 0.98
26 CHEMBL607707_1 0.98
27 ZINC39636228 0.97
28 ZINC12326842 0.97
29 CHEMBL607707 0.96
30 ZINC08789964 0.95
31 ZINC36750548 0.95
32 CHEMBL259247 0.91
33 CHEMBL495727_1 0.91
34 ZINC39654383 0.91
35 ZINC04164750 0.89
36 ZINC20504506 0.88
37 CHEMBL495727 0.88
38 ZINC39597032 0.84
39 ZINC40687408 0.79
40 ZINC15692115 0.77
41 ZINC12883449 0.74
42 ZINC02130274 0.68
43 ZINC39654361 0.67
44 ZINC39654112 0.65
45 ZINC39608898 0.61
46 ZINC39667061 0.56

Protein-ligand Complex Interaction information

Interaction Residue Residue_ID Residue_Atom Frequency
hydrogen bond MET 86 O 1
hydrogen bond TYR 21 O 1
hydrogen bond MET 86 N 1
hydrophobic contacts LEU 16 C 6
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrogen bond THR 83 O 1
hydrogen bond LYS 39 N 1
hydrophobic contacts LYS 39 C 6
hydrophobic contacts ILE 81 C 4
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts PHE 150 C 2
hydrophobic contacts THR 83 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts GLU 54 C 2
hydrogen bond TYR 88 O 1
halogenbond MET 86 O 1
hydrophobic contacts PHE 85 C 6
hydrophobic contacts LEU 16 C 6
hydrophobic contacts TYR 21 C 2
hydrogen bond ASP 93 O 1
hydrophobic contacts LEU 138 C 8
hydrophobic contacts TYR 21 C 8
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts VAL 24 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts MET 86 C 2
hydrophobic contacts PHE 150 C 2
hydrogen bond MET 86 O 1
hydrogen bond THR 87 O 1
hydrogen bond TYR 88 O 1
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond THR 83 O 1
hydrophobic contacts PHE 150 C 14
hydrophobic contacts TYR 21 C 10
hydrophobic contacts LEU 16 C 6
hydrophobic contacts VAL 24 C 6
hydrophobic contacts LYS 39 C 4
hydrophobic contacts LEU 138 C 4
hydrophobic contacts ALA 37 C 2
hydrogen bond TYR 88 O 1
hydrogen bond GLY 17 N 1
hydrogen bond GLY 89 N 1
hydrophobic contacts PHE 85 C 8
hydrophobic contacts LEU 16 C 8
hydrophobic contacts LEU 138 C 6
hydrophobic contacts TYR 21 C 6
hydrophobic contacts VAL 24 C 2
hydrophobic contacts TYR 21 C 6
hydrophobic contacts LEU 138 C 4
hydrophobic contacts PHE 85 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts LYS 39 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond MET 86 O 1
hydrogen bond THR 87 O 1
hydrogen bond TYR 88 O 1
hydrogen bond GLY 17 N 1
halogenbond ASP 93 O 1
hydrophobic contacts LEU 16 C 8
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts PHE 85 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond TYR 88 O 1
halogenbond MET 86 O 1
hydrophobic contacts LEU 16 C 6
hydrophobic contacts PHE 85 C 2
hydrophobic contacts TYR 21 C 2
hydrogen bond TYR 21 O 1
hydrogen bond ASP 93 O 1
hydrophobic contacts LEU 16 C 6
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts PHE 85 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts PHE 85 C 10
hydrophobic contacts TYR 21 C 10
hydrophobic contacts LEU 138 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts PHE 150 C 4
hydrophobic contacts ALA 148 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond ASP 149 N 1
hydrophobic contacts TYR 21 C 8
hydrophobic contacts LEU 138 C 6
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts PHE 150 C 4
hydrophobic contacts MET 86 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond TYR 21 O 1
hydrogen bond ASP 93 O 1
hydrophobic contacts LEU 16 C 6
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts PHE 85 C 2
hydrophobic contacts VAL 24 C 2
hydrogen bond MET 86 O 1
hydrogen bond THR 87 O 1
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts MET 86 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts PHE 85 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond THR 83 O 1
hydrophobic contacts TYR 21 C 6
hydrophobic contacts LYS 39 C 4
hydrophobic contacts LEU 138 C 4
hydrophobic contacts ILE 81 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond ASP 93 O 1
hydrophobic contacts TYR 21 C 8
hydrophobic contacts LYS 39 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond ASP 93 O 1
hydrogen bond TYR 21 O 1
hydrogen bond GLY 89 N 1
hydrophobic contacts PHE 85 C 8
hydrophobic contacts TYR 21 C 8
hydrophobic contacts LEU 16 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts PHE 150 C 2
hydrogen bond MET 86 O 1
hydrogen bond THR 87 O 1
hydrophobic contacts TYR 21 C 8
hydrophobic contacts VAL 24 C 4
hydrophobic contacts PHE 150 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond ASP 93 O 1
hydrophobic contacts LEU 16 C 6
hydrophobic contacts TYR 21 C 4
hydrophobic contacts VAL 67 C 4
hydrophobic contacts ALA 148 C 2
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond GLY 17 N 1
hydrophobic contacts PHE 85 C 4
hydrophobic contacts ILE 81 C 2
hydrophobic contacts LYS 39 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts THR 83 C 2
hydrogen bond ASP 93 O 1
hydrogen bond TYR 21 O 1
hydrogen bond ASN 90 N 1
halogenbond GLU 54 O 1
halogenbond ILE 81 O 1
hydrophobic contacts LEU 138 C 4
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts ALA 148 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts TYR 21 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond ASP 93 O 1
halogenbond THR 87 O 1
halogenbond TYR 88 O 1
hydrophobic contacts LEU 16 C 6
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts MET 86 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond GLU 26 O 1
hydrogen bond TYR 88 O 1
hydrophobic contacts LEU 16 C 6
hydrogen bond GLY 89 N 1
hydrophobic contacts LEU 16 C 8
hydrophobic contacts LEU 138 C 4
hydrophobic contacts PHE 85 C 4
hydrophobic contacts TYR 21 C 2
hydrogen bond MET 86 O 1
hydrogen bond MET 86 N 1
hydrophobic contacts TYR 21 C 10
hydrophobic contacts PHE 150 C 8
hydrophobic contacts LYS 39 C 6
hydrophobic contacts VAL 67 C 6
hydrophobic contacts LEU 16 C 6
hydrophobic contacts LEU 138 C 6
hydrophobic contacts VAL 24 C 6
hydrophobic contacts PHE 85 C 4
hydrophobic contacts ILE 81 C 2
hydrophobic contacts THR 83 C 2
hydrophobic contacts ALA 148 C 2
hydrogen bond GLU 26 O 1
hydrogen bond TYR 88 O 1
hydrogen bond THR 83 O 1
hydrophobic contacts TYR 21 C 6
hydrophobic contacts PHE 85 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LYS 39 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond MET 86 O 1
hydrogen bond GLU 84 O 1
hydrophobic contacts LEU 16 C 4
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 138 C 2
hydrogen bond MET 86 O 1
hydrogen bond GLY 17 N 1
hydrogen bond MET 86 N 1
hydrophobic contacts LEU 16 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond THR 83 O 1
hydrophobic contacts VAL 67 C 6
hydrophobic contacts LEU 138 C 2
hydrophobic contacts PHE 85 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts MET 86 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond LYS 15 O 1
hydrogen bond GLY 17 N 1
halogenbond GLU 26 O 1
hydrophobic contacts PHE 85 C 6
hydrophobic contacts LEU 16 C 6
hydrophobic contacts TYR 21 C 4
hydrogen bond THR 87 O 1
hydrophobic contacts LEU 16 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts MET 86 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond THR 87 O 1
halogenbond GLU 84 O 1
halogenbond THR 83 O 1
hydrophobic contacts PHE 150 C 6
hydrophobic contacts LYS 39 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond GLU 26 O 1
hydrophobic contacts TYR 21 C 8
hydrophobic contacts PHE 85 C 4
hydrophobic contacts PHE 150 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond THR 83 O 1
hydrogen bond MET 86 N 1
halogenbond TYR 21 O 1
hydrophobic contacts PHE 85 C 6
hydrophobic contacts ALA 148 C 2
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts ASP 93 C 2
hydrophobic contacts THR 83 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond GLU 26 O 2
hydrophobic contacts TYR 21 C 8
hydrophobic contacts PHE 85 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts PHE 150 C 2
hydrogen bond THR 87 O 1
halogenbond GLU 84 O 1
halogenbond THR 83 O 1
hydrophobic contacts PHE 150 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LYS 39 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond THR 87 O 1
hydrophobic contacts TYR 21 C 8
hydrophobic contacts LEU 16 C 6
hydrophobic contacts PHE 85 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond ASP 149 O 1
halogenbond ASP 93 O 1
hydrophobic contacts TYR 21 C 6
hydrophobic contacts ILE 81 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LYS 39 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrophobic contacts GLU 54 C 2
hydrogen bond TYR 21 O 1
hydrogen bond GLU 84 O 1
hydrogen bond THR 83 O 1
hydrophobic contacts TYR 21 C 10
hydrophobic contacts PHE 150 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts VAL 67 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LYS 39 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts THR 83 C 2
hydrophobic contacts MET 86 C 2
hydrogen bond THR 87 O 1
hydrogen bond TYR 88 O 1
hydrophobic contacts PHE 85 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LYS 39 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond MET 86 O 1
hydrogen bond GLY 17 N 1
hydrogen bond MET 86 N 1
hydrophobic contacts LEU 16 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts VAL 24 C 2
hydrophobic contacts ALA 37 C 2
hydrophobic contacts VAL 67 C 2
hydrogen bond MET 86 O 1
hydrophobic contacts LYS 39 C 6
hydrophobic contacts VAL 24 C 6
hydrophobic contacts PHE 85 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LEU 138 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond MET 86 O 1
hydrogen bond THR 87 O 1
hydrogen bond ASP 93 O 1
hydrophobic contacts LEU 138 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LYS 39 C 2
hydrophobic contacts PHE 85 C 2
hydrophobic contacts LEU 16 C 2
hydrophobic contacts THR 83 C 2
hydrophobic contacts ALA 37 C 2
hydrogen bond THR 87 O 1
hydrogen bond ASP 93 O 1
hydrophobic contacts LEU 138 C 4
hydrophobic contacts LEU 16 C 4
hydrophobic contacts VAL 24 C 4
hydrophobic contacts TYR 21 C 4
hydrophobic contacts LYS 39 C 2
hydrophobic contacts PHE 85 C 2
hydrophobic contacts PHE 150 C 2
hydrophobic contacts ALA 37 C 2

Interaction frequency analysis for reference

Interaction Residue Residue_ID Residue_Atom Frequency
hydrogen bond MET 86 O 110
hydrogen bond THR 87 O 60
hydrogen bond THR 83 O 54
hydrogen bond GLY 17 N 46
hydrogen bond TYR 88 O 37
hydrogen bond GLU 26 O 33
hydrogen bond ASP 93 O 24
hydrogen bond ASP 149 O 23
hydrogen bond GLU 54 O 23
hydrogen bond PHE 150 N 15
hydrogen bond GLU 84 O 15
hydrogen bond HIS 14 N 14
hydrogen bond TYR 21 O 13
hydrogen bond GLY 89 N 11
hydrogen bond ASN 90 N 11
hydrogen bond ASP 149 N 10
hydrogen bond MET 86 N 8
hydrogen bond LYS 39 N 7
hydrogen bond GLN 20 N 6
hydrogen bond ILE 81 O 4
hydrogen bond ALA 37 O 2
hydrogen bond THR 35 O 1
hydrogen bond GLY 18 N 1
hydrogen bond GLY 89 O 1
hydrogen bond VAL 38 N 1
hydrogen bond LYS 15 O 1
hydrogen bond GLY 17 O 1
hydrophobic contacts LEU 16 C 998
hydrophobic contacts TYR 21 C 974
hydrophobic contacts PHE 85 C 656
hydrophobic contacts VAL 24 C 548
hydrophobic contacts LEU 138 C 492
hydrophobic contacts PHE 150 C 452
hydrophobic contacts ALA 37 C 392
hydrophobic contacts LYS 39 C 322
hydrophobic contacts VAL 67 C 182
hydrophobic contacts ILE 81 C 166
hydrophobic contacts THR 83 C 106
hydrophobic contacts MET 86 C 76
hydrophobic contacts ALA 148 C 18
hydrophobic contacts GLU 54 C 12
hydrophobic contacts THR 35 C 6
hydrophobic contacts THR 87 C 6
halogenbond ALA 37 O 22
halogenbond THR 83 O 19
halogenbond ASP 149 O 18
halogenbond ASP 93 O 16
halogenbond GLU 54 O 14
halogenbond MET 86 O 12
halogenbond ILE 81 O 10
halogenbond GLU 26 O 10
halogenbond THR 87 O 10
halogenbond TYR 88 O 7
halogenbond GLY 17 O 5
halogenbond TYR 21 O 4
halogenbond LEU 16 O 2
halogenbond LYS 15 O 2
halogenbond GLU 84 O 1
halogenbond THR 35 O 1

Cluster

  • Clustering Failed