• Molecular NameCysteamine
  • SynonymN/A
  • Weight78.157
  • Drugbank_IDDB00847
  • ACS_NO60-23-1
  • Show 3D model
  • LogP (experiment)-0.196
  • LogP (predicted, AB/LogP v2.0)-0.02
  • pkaN/A
  • LogD (pH=7, predicted)-2.62
  • Solubility (experiment)Soluble
  • LogS (predicted, ACD/Labs)(ph=7)1.11
  • LogSw (predicted, AB/LogsW2.0)25.33
  • Sw (mg/ml) (predicted, ACD/Labs)233.19
  • No.of HBond Donors2
  • No.of HBond Acceptors1
  • No.of Rotatable Bonds1
  • TPSA64.82
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyRadiation-Protective Agents
  • Absorption_value0.0
  • Absorption (description)N/A
  • Caco_20.0
  • Bioavailability0.0
  • Protein binding52.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmCysteamine is an aminothiol that participates within lysosomes in a thiol-disulfide interchange reaction converting cystine into cysteine and cysteine-cysteamine mixed disulfide, both of which can exit the lysosome in patients with cystinosis.
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose may include convulsions (seizures), increased thirst and unusual tiredness or weakness.
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=250 mg/kg(ip); LD50=450 mg/kg(intraperitoneal); LD50=625 mg/kg(peroral)