Searching results

Approved Drugs

Name:  Carfilzomib

Formula:  C40H57N5O7

Similarity:  0.5909090909090909

Inhibitors

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-(4-chlorophenyl)piperidine-1,4-dicarboxamide

Formula:  C37H50ClN5O6

Similarity:  0.9424460431654677

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N4-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N1-(4-methoxyphenyl)piperidine-1,4-dicarboxamide

Formula:  C38H53N5O7

Similarity:  0.8958333333333334

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-(4-fluorophenyl)piperidine-1,4-dicarboxamide

Formula:  C37H50FN5O6

Similarity:  0.8620689655172413

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-4-[(4-chlorophenyl)carbamoylamino]piperidine-1-carboxamide

Formula:  C37H51ClN6O6

Similarity:  0.8571428571428571

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-(4-methoxyphenyl)piperidine-1,4-dicarboxamide

Formula:  C38H53N5O7

Similarity:  0.8445945945945946

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N3-(4-chlorophenyl)piperidine-1,3-dicarboxamide

Formula:  C37H50ClN5O6

Similarity:  0.8367346938775511

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N4-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N1-(4-chlorophenyl)piperazine-1,4-dicarboxamide

Formula:  C36H49ClN6O6

Similarity:  0.8367346938775511

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-4-[(4-chlorobenzoyl)amino]piperidine-1-carboxamide

Formula:  C37H50ClN5O6

Similarity:  0.8120805369127517

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-(4-pyridyl)piperidine-1,4-dicarboxamide

Formula:  C36H50N6O6

Similarity:  0.8108108108108109

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-(3-pyridyl)piperidine-1,4-dicarboxamide

Formula:  C36H50N6O6

Similarity:  0.7866666666666666

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N4-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N1-pyrazin-2-yl-piperidine-1,4-dicarboxamide

Formula:  C35H49N7O6

Similarity:  0.7866666666666666

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-(4-phenylphenyl)piperidine-1,4-dicarboxamide

Formula:  C43H55N5O6

Similarity:  0.7763975155279503

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-methyl-piperidine-1,4-dicarboxamide

Formula:  C32H49N5O6

Similarity:  0.7746478873239436

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-4-[(4-methoxyphenyl)carbamoylamino]piperidine-1-carboxamide

Formula:  C38H54N6O7

Similarity:  0.7692307692307693

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-isoxazol-3-yl-piperidine-1,4-dicarboxamide

Formula:  C34H48N6O7

Similarity:  0.7666666666666667

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-thiazol-2-yl-piperidine-1,4-dicarboxamide

Formula:  C34H48N6O6S

Similarity:  0.7549668874172185

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N4-(1,3-benzothiazol-2-yl)-N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]piperidine-1,4-dicarboxamide

Formula:  C38H50N6O6S

Similarity:  0.7531645569620253

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N4-(4-benzoylphenyl)-N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]piperidine-1,4-dicarboxamide

Formula:  C44H55N5O7

Similarity:  0.7530120481927711

Relative Targets:   Proteasome subunit beta type-2  |

Name:  N1-[(1S)-1-[[(1S)-1-benzyl-2-[[(1S)-3-methyl-1-[(2R)-2-methyloxirane-2-carbonyl]butyl]amino]-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]-N4-pyrimidin-2-yl-piperidine-1,4-dicarboxamide

Formula:  C35H49N7O6

Similarity:  0.7516339869281046

Relative Targets:   Proteasome subunit beta type-2  |