VGSC-DB Target ID	NAT008
Name	Sodium channel protein type 10 subunit alpha
Synonyms	Peripheral nerve sodium channel 3 Sodium channel protein type X subunit alpha Voltage-gated sodium channel subunit alpha Nav1.8
Description	Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
Organism	Human, Rat
PDB ID	None
UniProt	Q9Y5Y9, Q62968

VGSC-DB ID	Sructure	PubChem CID	Molecular Formula	IC50/EC50* (nM)	Binding Site	Organism	Article DOI