VGSC-DB Target ID	NAT002
Name	Sodium channel protein type 2 subunit alpha
Synonyms	Sodium channel protein brain II subunit alpha Sodium channel protein type II subunit alpha Voltage-gated sodium channel subunit alpha Nav1.2
Description	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. Implicated in the regulation of hippocampal replay occurring within sharp wave ripples (SPW-R) important for memory (By similarity).
Organism	Human, Rat
PDB ID	6J8E
UniProt	Q99250, P04775

VGSC-DB ID	Sructure	PubChem CID	Molecular Formula	IC50/EC50* (nM)	Binding Site	Organism	Article DOI