• Molecular NameClotrimazole
  • SynonymChlotrimazole; Clotrimazol
  • Weight344.845
  • Drugbank_IDDB00257
  • ACS_NO23593-75-1
  • Show 3D model
  • LogP (experiment)4.99
  • LogP (predicted, AB/LogP v2.0)5.08
  • pkaN/A
  • LogD (pH=7, predicted)4.79
  • Solubility (experiment)Slightly soluble
  • LogS (predicted, ACD/Labs)(ph=7)-4.82
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors0
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds4
  • TPSA17.82
  • StatusFDA approved
  • Administrationtopical
  • PharmacologyAn antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.
  • Absorption_valueN/A
  • Absorption (description)Poorly and erratically absorbed orally, minimal vaginal or topical absorption.
  • Caco_2N/A
  • Bioavailability0.0
  • Protein binding90.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (metabolized to inactive metabolites)
  • Half life2 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A