• Molecular NameDibucaine
  • SynonymNA
  • Weight343.471
  • Drugbank_IDDB00527
  • ACS_NO85-79-0
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)4.01
  • pkaN/A
  • LogD (pH=7, predicted)1.87
  • Solubility (experiment)0.0681 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.34
  • LogSw (predicted, AB/LogsW2.0)0.24
  • Sw (mg/ml) (predicted, ACD/Labs)0.11
  • No.of HBond Donors1
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds10
  • TPSA54.46
  • StatusFDA approved
  • AdministrationTopical, intravenous (equine euthanasia)
  • PharmacologyAn amide local anesthetic. It is the active ingredient in some topical hemorrhoid creams such as Proctosedyl.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A