- Molecular NameMethantheline
- SynonymBanthine Bromide; Methantheline Bromide; Methanthelinium; Methanthelinium Bromide; Methanthelinum; Methanthine Bromide; MTB 51
- Weight340.443
- Drugbank_IDDB00940
- ACS_NO5818-17-7
- Show 2D model
- LogP (experiment)N/A
- LogP (predicted, AB/LogP v2.0)-0.24
- pkaN/A
- LogD (pH=7, predicted)-0.24
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)-0.34
- LogSw (predicted, AB/LogsW2.0)7.29
- Sw (mg/ml) (predicted, ACD/Labs)154.72
- No.of HBond Donors0
- No.of HBond Acceptors4
- No.of Rotatable Bonds7
- TPSA35.53
- StatusFDA approved; US withdrawn
- AdministrationN/A
- PharmacologyAn antimuscarinic.
- Absorption_valueN/A
- Absorption (description)Rapidly absorbed.
- Caco_2N/A
- BioavailabilityN/A
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmHepatic, by enzymatic hydrolysis.
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicitySymptoms of overdose: blurred vision (continuing) or changes in near vision, clumsiness or unsteadiness, confusion, convulsions, difficulty in breathing, muscle weakness (severe), or tiredness (severe), dizziness, drowsiness (severe), dryness of mouth, nose, or throat (severe), fast heartbeat, fever, hallucinations, slurred speech, unusual excitement, nervousness, restlessness, or irritability, unusual warmth, dryness, and flushing of skin.
- LD50 (rat)N/A
- LD50 (mouse)LD50=1000