• Molecular NameLisuride
  • SynonymNA
  • Weight338.455
  • Drugbank_IDDB00589
  • ACS_NO18016-80-3
  • Show 3D model
  • LogP (experiment)2.95
  • LogP (predicted, AB/LogP v2.0)3.2
  • pkaN/A
  • LogD (pH=7, predicted)2.9
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.25
  • LogSw (predicted, AB/LogsW2.0)0.11
  • Sw (mg/ml) (predicted, ACD/Labs)0.1
  • No.of HBond Donors2
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds3
  • TPSA51.37
  • StatusFDA approved
  • AdministrationOral, subcutaneous, transdermal
  • PharmacologyAn anti-Parkinson's drug of the iso-ergoline class, chemically related to the dopaminergic ergoline Parkinson's drugs.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability14.0
  • Protein binding0.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life2 h
  • Excretionrenal and biliary in equal amounts
  • Urinary Excretion88~100
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A