• Molecular NameBromfenac
  • SynonymBromfenac sodium
  • Weight334.169
  • Drugbank_IDDB00963
  • ACS_NO91714-94-2
  • Show 3D model
  • LogP (experiment)3.775
  • LogP (predicted, AB/LogP v2.0)3.09
  • pka4.3
  • LogD (pH=7, predicted)0.28
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.08
  • LogSw (predicted, AB/LogsW2.0)0.18
  • Sw (mg/ml) (predicted, ACD/Labs)0.08
  • No.of HBond Donors3
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds4
  • TPSA80.39
  • StatusFDA approved
  • AdministrationOral (discontinued) ophthalmic
  • PharmacologyA non-steroidal anti-inflammatory drug (NSAID)
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability79.0
  • Protein binding83.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmBromfenac is secreted from the organism conjugated with UDP-D-glucose. It also transforms spontaneously into cyclic amide with further oxidation and conjugation.
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A