• Molecular NameEtonogestrel
  • Synonymetonogestrel
  • Weight324.464
  • Drugbank_IDDB00294
  • ACS_NO54048-10-1
  • Show 2D model
  • LogP (experiment)3.16
  • LogP (predicted, AB/LogP v2.0)3.29
  • pkaN/A
  • LogD (pH=7, predicted)3.29
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-4.85
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds2
  • TPSA37.3
  • StatusFDA approved
  • AdministrationSubdermal as slow-release implant
  • PharmacologyA molecule used in hormonal contraceptives, most notably the subdermal implant Implanon and the contraceptive vaginal ring NuvaRing.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (P450 3A4)
  • Half life25 h
  • ExcretionUrinary (majority) and fecal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A