• Molecular NameQuinidine
  • SynonymQuinidine Gluconate; Quinidine Sulfate
  • Weight324.424
  • Drugbank_IDDB00908
  • ACS_NO56-54-2
  • Show 2D model
  • LogP (experiment)2.64
  • LogP (predicted, AB/LogP v2.0)2.89
  • pka4.2, 8.8
  • LogD (pH=7, predicted)1.32
  • Solubility (experiment)0.142 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.2
  • LogSw (predicted, AB/LogsW2.0)0.28
  • Sw (mg/ml) (predicted, ACD/Labs)0.15
  • No.of HBond Donors1
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds4
  • TPSA45.59
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA pharmaceutical agent that acts as a class I antiarrhythmic agent (Ia) in the heart. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree.
  • Absorption_value80.0
  • Absorption (description)N/A
  • Caco_2-4.69
  • Bioavailability75.0
  • Protein binding87.0
  • Volume of distribution (VD)3.5 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmMetabolically cleared primarily by CYP3A
  • Half life6.2 h
  • ExcretionRenal
  • Urinary Excretion18
  • Clerance4.7 ml/min/kg
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=594