- Molecular NameTenoxicam
- SynonymTenoxicamum [INN-Latin]
- Weight321.381
- Drugbank_IDDB00469
- ACS_NO59804-37-4
- Show 2D model
- LogP (experiment)1.219
- LogP (predicted, AB/LogP v2.0)1.9
- pka5.3; 1.1
- LogD (pH=7, predicted)1.9
- Solubility (experiment)0.045 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)-4.15
- LogSw (predicted, AB/LogsW2.0)0.06
- Sw (mg/ml) (predicted, ACD/Labs)0.02
- No.of HBond Donors1
- No.of HBond Acceptors6
- No.of Rotatable Bonds2
- TPSA115.99
- StatusFDA approved
- AdministrationThe recommended dose of tenoxicam ranges from 10 mg to 20 mg taken once daily. This medication should be taken at the same time each day and immediately after a meal or after food to avoid stomach upset.
- PharmacologyA non-steroidal anti-inflammatory drug.
- Absorption_value100.0
- Absorption (description)Oral absorption of tenoxicam is rapid and complete (absolute bioavailability 100%).
- Caco_2N/A
- Bioavailability80.0
- Protein binding98.5
- Volume of distribution (VD)0.13 L/kg
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmTenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam).
- Half life60~70 h
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A