• Molecular NameNorfloxacin
  • SynonymNA
  • Weight319.336
  • Drugbank_IDDB01059
  • ACS_NO70458-96-7
  • Show 2D model
  • LogP (experiment)-1.03
  • LogP (predicted, AB/LogP v2.0)-0.92
  • pkaN/A
  • LogD (pH=7, predicted)-3.1
  • Solubility (experiment)0.28 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-2.37
  • LogSw (predicted, AB/LogsW2.0)0.7
  • Sw (mg/ml) (predicted, ACD/Labs)1.37
  • No.of HBond Donors2
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds3
  • TPSA72.88
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA drug is used to treat common as well as complicated urinary tract infections.
  • Absorption_value71.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability35.0
  • Protein binding12.5
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life3~4 h
  • ExcretionRenal and fecal; Urine excretion=35
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityThe most common adverse experiences (>1.0%) were: dizziness (2.6%), nausea (2.6%), headache (2.0%), and abdominal cramping (1.6%).
  • LD50 (rat)LD50=314 (iv)
  • LD50 (mouse)LD50>4000\