• Molecular NameDexbrompheniramine
  • SynonymD-Brompheniramine; Parabromdylamine; Parabromodylamine
  • Weight319.246
  • Drugbank_IDDB00405
  • ACS_NO132-21-8
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.24
  • pkaN/A
  • LogD (pH=7, predicted)1.12
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.83
  • LogSw (predicted, AB/LogsW2.0)0.82
  • Sw (mg/ml) (predicted, ACD/Labs)0.28
  • No.of HBond Donors0
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA16.13
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn antihistamine used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine.
  • Absorption_valueN/A
  • Absorption (description)Antihistamines are well absorbed from the gastrointestinal tract after oral administration.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (cytochrome P-450 system), some renal.
  • Half life25 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySigns of an overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A