• Molecular NameArbutamine
  • SynonymNA
  • Weight317.385
  • Drugbank_IDDB01102
  • ACS_NO128470-16-6
  • Show 2D model
  • LogP (experiment)2.611
  • LogP (predicted, AB/LogP v2.0)1.78
  • pkaN/A
  • LogD (pH=7, predicted)0.01
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.76
  • LogSw (predicted, AB/LogsW2.0)37.78
  • Sw (mg/ml) (predicted, ACD/Labs)0.12
  • No.of HBond Donors5
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds8
  • TPSA92.95
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA cardiac stimulant.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding58.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmPrimarily metabolized to methoxyarbutamine. Another possible metabolite is ketoarbutamine. The metabolites of arbutamine appear to have less pharmacological activity and a longer half-life and than the parental drug.
  • Half lifeElimination half-life is approximately 8 minutes.
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A