• Molecular NameValdecoxib
  • Synonymvaldecoxib
  • Weight314.365
  • Drugbank_IDN/A
  • ACS_NO181695-72-7
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.17
  • pkaN/A
  • LogD (pH=7, predicted)3.17
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.62
  • LogSw (predicted, AB/LogsW2.0)0.01
  • Sw (mg/ml) (predicted, ACD/Labs)0.08
  • No.of HBond Donors2
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds3
  • TPSA94.57
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability83.0
  • Protein binding98.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (CYP3A4 and 2C9 involved)
  • Half life8 to 11 hours
  • ExcretionRenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms following acute NSAID overdoses are usually limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain, which are generally reversible with supportive care. Gastrointestinal bleeding can occur. Hypertension, acute renal failure, respiratory depression and coma may occur, but are rare.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A