• Molecular NameDiphenidol
  • SynonymDifenidol; Difenidol HCl; Difenidol hydrochloride; Difenidolo [DCIT]; Difenidolum [INN-Latin]; Diphenidol HCl; Diphenidol hydrochloride
  • Weight309.453
  • Drugbank_IDDB01231
  • ACS_NO972-02-1
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.68
  • pkaN/A
  • LogD (pH=7, predicted)1.2
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.76
  • LogSw (predicted, AB/LogsW2.0)0.23
  • Sw (mg/ml) (predicted, ACD/Labs)0.19
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds6
  • TPSA23.47
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn muscarinic antagonist employed as an antiemetic and as an antivertigo agent.
  • Absorption_valueN/A
  • Absorption (description)Well absorbed from gastrointestinal tract following oral administration.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life4 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose include drowsiness (severe); shortness of breath or troubled breathing; unusual tiredness or weakness (severe).
  • LD50 (rat)N/A
  • LD50 (mouse)N/A