- Molecular NameFenoterol
- SynonymFenoterolum [inn-latin]; Phenoterol
- Weight303.358
- Drugbank_IDDB01288
- ACS_NO13392-18-2
- Show 3D model
- LogP (experiment)0.83
- LogP (predicted, AB/LogP v2.0)1.42
- pka8.5, 10.0
- LogD (pH=7, predicted)0.52
- Solubility (experiment)100 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)-1.42
- LogSw (predicted, AB/LogsW2.0)35.32
- Sw (mg/ml) (predicted, ACD/Labs)2.71
- No.of HBond Donors5
- No.of HBond Acceptors5
- No.of Rotatable Bonds6
- TPSA92.95
- StatusFDA approved
- AdministrationInhaled
- PharmacologyAn asthma medication designed to open up the airways to the lungs. It is classed as a beta agonist.
- Absorption_value60.0
- Absorption (description)Rapidly but incompletely absorbed after inhalation or oral administration.
- Caco_2N/A
- Bioavailability2.0
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmIt undergoes extensive first-pass metabolism by sulfate conjugation.
- Half life6~7 h
- ExcretionAbout 35% of an oral dose is excreted in the urine in 24 h, mainly as the inactive sulfate conjugate, and less than 2% as unchanged drug; about 40% of an oral dose is eliminated in the faeces.
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A