• Molecular NameIcosapent
  • SynonymEicosapentaenoic acid; EPA; Icosapentaenoic acid; Timnodonic acid
  • Weight302.458
  • Drugbank_IDDB00159
  • ACS_NO10417-94-4, 1553-41-9, 25377-48-4
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)5.92
  • pkaN/A
  • LogD (pH=7, predicted)3.82
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.25
  • LogSw (predicted, AB/LogsW2.0)0.09
  • Sw (mg/ml) (predicted, ACD/Labs)0.02
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds13
  • TPSA37.3
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyEicosanoids are chemical messengers derived from 20-carbon polyunsaturated fatty acids that play critical roles in immune and inflammatory responses.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmEicosapentaenoic acid is oxidated by CYP2E1, CYP1A1, CYP2C8.
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityAdverse events occured in patients treated with Omacor include flu syndrom, infection, flu syndrome, eructation.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A