• Molecular NameAllylestrenol
  • SynonymNA
  • Weight300.486
  • Drugbank_IDDB01431
  • ACS_NO432-60-0
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)5.08
  • pkaN/A
  • LogD (pH=7, predicted)5.08
  • Solubility (experiment)Insoluble
  • LogS (predicted, ACD/Labs)(ph=7)-6.23
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors1
  • No.of HBond Acceptors1
  • No.of Rotatable Bonds2
  • TPSA20.23
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAllylestrenol is a progestogen structurally related to progesterone that has been given in threatened and recurrent miscarriage, and to prevent premature labour. However, with the exception of proven progesterone deficiency, such use is no longer recommended. In threatened miscarriage in progesterone-deficient women a suggested dose is 5 mg three times daily by mouth for 5 to 7 days
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life9.46 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A