- Molecular NameAspartame
- Synonym1-Methyl N-L-alpha-aspartyl-L-phenylalanate; 1-Methyl N-L-alpha-aspartyl-L-phenylalanine; 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester; 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, stereoisomer; 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid; APM; Asp-phe-ome; Aspartam [INN-French]; Aspartame [USAN:BAN:INN]; Aspartamo [INN-Spanish]; Aspartamum [INN-Latin]; Aspartylphenylalanine methyl ester; Dipeptide sweetener; L-Aspartyl-L-phenylalanine methyl ester; Methyl aspartylphenylalanate; Methyl L-alpha-aspartyl-L-phenylalanate; Methyl L-aspartyl-L-phenylalanine; Methyl N-L-alpha-aspartyl-L-phenylalaninate; N-L-alpha-Aspartyl-L-phenylalanine 1-methyl ester; Sweet dipeptide
- Weight294.307
- Drugbank_IDDB00168
- ACS_NO22839-47-0
- Show 3D model
- LogP (experiment)N/A
- LogP (predicted, AB/LogP v2.0)-0.03
- pkaN/A
- LogD (pH=7, predicted)-0.09
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)-0.97
- LogSw (predicted, AB/LogsW2.0)4.38
- Sw (mg/ml) (predicted, ACD/Labs)16.99
- No.of HBond Donors4
- No.of HBond Acceptors7
- No.of Rotatable Bonds8
- TPSA118.72
- StatusFDA approved
- AdministrationN/A
- PharmacologyN/A
- Absorption_valueN/A
- Absorption (description)Absorbed in the small intestine, aspartame is metabolized and absorbed very quickly.
- Caco_2N/A
- BioavailabilityN/A
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmUpon ingestion, aspartame breaks down into natural residual components, including aspartic acid, phenylalanine, methanol, and further breakdown products including formaldehyde,[21] formic acid, and a diketopiperazine.
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A