• Molecular NameTerbinafine
  • Synonymterbinafine; Terbinafine HCl; Terbinafine hydrochloride; Ternbinafine HCl
  • Weight291.438
  • Drugbank_IDDB00857
  • ACS_NO91161-71-6
  • Show 2D model
  • LogP (experiment)6.0
  • LogP (predicted, AB/LogP v2.0)5.47
  • pka8.5
  • LogD (pH=7, predicted)5.12
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-6.09
  • LogSw (predicted, AB/LogsW2.0)0.0
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors0
  • No.of HBond Acceptors1
  • No.of Rotatable Bonds6
  • TPSA3.24
  • StatusFDA approved
  • AdministrationOral, topical
  • PharmacologyA synthetic allylamine antifungal.
  • Absorption_value80.0
  • Absorption (description)Readily absorbed from gastrointestinal tract.
  • Caco_2N/A
  • Bioavailability49.0
  • Protein binding99.0
  • Volume of distribution (VD)14 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life36 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A