• Molecular NameDyclonine
  • SynonymNA
  • Weight289.419
  • Drugbank_IDDB00645
  • ACS_NO586-60-7
  • Show 2D model
  • LogP (experiment)3.931
  • LogP (predicted, AB/LogP v2.0)4.03
  • pkaN/A
  • LogD (pH=7, predicted)2.09
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-2.08
  • LogSw (predicted, AB/LogsW2.0)0.24
  • Sw (mg/ml) (predicted, ACD/Labs)0.06
  • No.of HBond Donors0
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds8
  • TPSA29.54
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn oral anaesthetic found in Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life30~60 min
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose include cardiovascular system depression, CNS toxicity, and methemoglobinemia.
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=130 (intraperitoneal)