• Molecular NameProcyclidine
  • SynonymProciclidina [INN-Spanish]; Procyclidinum [INN-Latin]
  • Weight287.447
  • Drugbank_IDDB00387
  • ACS_NO77-37-2
  • Show 2D model
  • LogP (experiment)4.34
  • LogP (predicted, AB/LogP v2.0)4.18
  • pka8.8
  • LogD (pH=7, predicted)1.58
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.25
  • LogSw (predicted, AB/LogsW2.0)0.54
  • Sw (mg/ml) (predicted, ACD/Labs)0.31
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA23.47
  • StatusFDA approved
  • AdministrationOral, IM, IV
  • PharmacologyAn anticholinergic drug principally used for the treatment of 1. Drug-induced parkinsonism, akathisia and acute dystonia; 2. Parkinson disease; and; 3. Idiopathic or secondary dystonia.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability79.0
  • Protein binding100.0
  • Volume of distribution (VD)1 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life12 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=60 mg/kg (IV)