• Molecular NameNaftifine
  • SynonymNA
  • Weight287.406
  • Drugbank_IDDB00735
  • ACS_NO65472-88-0
  • Show 2D model
  • LogP (experiment)5.62
  • LogP (predicted, AB/LogP v2.0)5.2
  • pkaN/A
  • LogD (pH=7, predicted)4.85
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.88
  • LogSw (predicted, AB/LogsW2.0)0.01
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors0
  • No.of HBond Acceptors1
  • No.of Rotatable Bonds5
  • TPSA3.24
  • StatusFDA approved
  • AdministrationTopical
  • PharmacologyAn allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (fungal infections).
  • Absorption_valueN/A
  • Absorption (description)Following single topical applications of 3H-labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A