• Molecular NameRitodrine
  • SynonymRitodrina [INN-Spanish]; Ritodrine Hcl; Ritodrine Hydrochloride; Ritodrinium [INN-Latin]
  • Weight287.359
  • Drugbank_IDDB00867
  • ACS_NO26652-09-5
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)1.65
  • pka9
  • LogD (pH=7, predicted)-0.3
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.42
  • LogSw (predicted, AB/LogsW2.0)28.81
  • Sw (mg/ml) (predicted, ACD/Labs)1.58
  • No.of HBond Donors4
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds6
  • TPSA72.72
  • StatusFDA approved
  • AdministrationOral, parenteral
  • PharmacologyA tocolytic drug, used to stop premature labor.
  • Absorption_value95.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability30.0
  • Protein binding32.0
  • Volume of distribution (VD)0.6~0.9 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life1~2 h; a longer elimination half-life of about 15 to 20 h has also been reported.
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)LD50=85 mg/kg (IV)
  • LD50 (mouse)LD50=540 mg/kg