• Molecular NameLevallorphan
  • SynonymNA
  • Weight283.415
  • Drugbank_IDDB00504
  • ACS_NO152-02-3
  • Show 3D model
  • LogP (experiment)3.48
  • LogP (predicted, AB/LogP v2.0)3.65
  • pka4.5, 6.9
  • LogD (pH=7, predicted)2.56
  • Solubility (experiment)0.633 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.93
  • LogSw (predicted, AB/LogsW2.0)0.19
  • Sw (mg/ml) (predicted, ACD/Labs)0.27
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds2
  • TPSA23.47
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA drug which acts as an opioid mixed agonist-antagonist, with mainly antagonist effects. It is derived from the morphinan family of drugs.
  • Absorption_valueN/A
  • Absorption (description)Rapidly absorbed.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmIt is metabolised by N-dealkylation and glucuronic acid conjugation.
  • Half life1 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityThe estimated minimum lethal dose is 0.2 g or 2 g for an addict.
  • LD50 (rat)LD50=109mg/kg
  • LD50 (mouse)N/A