• Molecular NameColestipol
  • SynonymColestipolum [INN-Latin]
  • Weight281.832
  • Drugbank_IDDB00375
  • ACS_NO50925-79-6
  • Show 3D model
  • LogP (experiment)-4.648
  • LogP (predicted, AB/LogP v2.0)-2.58
  • pkaN/A
  • LogD (pH=7, predicted)-6.43
  • Solubility (experiment)Insoluble
  • LogS (predicted, ACD/Labs)(ph=7)0.72
  • LogSw (predicted, AB/LogsW2.0)392.44
  • Sw (mg/ml) (predicted, ACD/Labs)1000.0
  • No.of HBond Donors0
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds12
  • TPSA16.2
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA bile acid sequestrant.
  • Absorption_value0.0
  • Absorption (description)Not absorbed from the gastrointestinal tract.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose may include eye irritation, constipation, abdominal cramps, nausea, vomiting, diarrhea, and hypersensitivity. However, as colestipol is not absorbed, the risk of systemic toxicity is low.
  • LD50 (rat)> 1000 mg/kg
  • LD50 (mouse)N/A