• Molecular NameSulfametopyrazine
  • SynonymNA
  • Weight280.308
  • Drugbank_IDDB00664
  • ACS_NO152-47-6, 5175-55-3
  • Show 2D model
  • LogP (experiment)0.85
  • LogP (predicted, AB/LogP v2.0)0.44
  • pka7.0
  • LogD (pH=7, predicted)-0.53
  • Solubility (experiment)4.03 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.54
  • LogSw (predicted, AB/LogsW2.0)0.84
  • Sw (mg/ml) (predicted, ACD/Labs)1.04
  • No.of HBond Donors3
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds4
  • TPSA115.58
  • StatusFDA approved; withdrawn
  • AdministrationN/A
  • PharmacologySulfametopyrazine is a sulfonamide antibiotic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding72.5
  • Volume of distribution (VD)0.2~0.3 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life2~4 days
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A