• Molecular NameSulfamethazine
  • SynonymNA
  • Weight278.336
  • Drugbank_IDDB01582
  • ACS_NO57-68-1
  • Show 2D model
  • LogP (experiment)0.9
  • LogP (predicted, AB/LogP v2.0)0.32
  • pka7.4 (25°)
  • LogD (pH=7, predicted)0.1
  • Solubility (experiment)1.49 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-2.8
  • LogSw (predicted, AB/LogsW2.0)0.51
  • Sw (mg/ml) (predicted, ACD/Labs)0.32
  • No.of HBond Donors3
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds3
  • TPSA106.35
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA sulfonamide antibacterial.
  • Absorption_value95.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability86.5
  • Protein binding75.0
  • Volume of distribution (VD)0.6 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeDerived from urinary excretion data, 1 to 5 h for rapid acetylators and 3 to 11 h (mean 6) for slow acetylators.
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A