• Molecular NameClenbuterol
  • SynonymClenbuterolum [inn-latin]
  • Weight277.195
  • Drugbank_IDDB01407
  • ACS_NO37148-27-9
  • Show 3D model
  • LogP (experiment)2.87
  • LogP (predicted, AB/LogP v2.0)2.61
  • pkaN/A
  • LogD (pH=7, predicted)0.07
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.33
  • LogSw (predicted, AB/LogsW2.0)1.18
  • Sw (mg/ml) (predicted, ACD/Labs)0.58
  • No.of HBond Donors4
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds4
  • TPSA58.28
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA drug prescribed to sufferers of breathing disorders as a decongestant and bronchodilator.
  • Absorption_valueN/A
  • Absorption (description)Clenbuterol is rapidly and almost completely absorbed after oral administration
  • Caco_2N/A
  • Bioavailability80.0
  • Protein binding93.5
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmExtensively metabolised by first-pass sulfation.
  • Half life35 h
  • ExcretionExcretion is mainly via the kidneys for intravenous administration and biotransformation for oral administration.
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityA 21-year-old body builder drank orange juice ‘spiked’ with 48 tablets (4.8 g) of clenbuterol and admitted with tachycardia, headache, dizziness, tremor, sweats, muscle weakness and agitation. [Z. Chodorowski and J. Sein Anand,Przegl. Lek.,1997, 54, 763–764].
  • LD50 (rat)N/A
  • LD50 (mouse)N/A