• Molecular NameRolipram
  • SynonymNA
  • Weight275.348
  • Drugbank_IDN/A
  • ACS_NO61413-54-5
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)2.06
  • pkaN/A
  • LogD (pH=7, predicted)2.06
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-3.39
  • LogSw (predicted, AB/LogsW2.0)0.63
  • Sw (mg/ml) (predicted, ACD/Labs)0.11
  • No.of HBond Donors1
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds4
  • TPSA47.56
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA PDE4-inhibitor. Like most PDE4-inhibitors, it is an anti-inflammatory drug.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability75.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life1~3 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A