• Molecular NameTilidine
  • SynonymNA
  • Weight271.404
  • Drugbank_IDN/A
  • ACS_NO51931-66-9
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.5
  • pkaN/A
  • LogD (pH=7, predicted)2.51
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.55
  • LogSw (predicted, AB/LogsW2.0)0.79
  • Sw (mg/ml) (predicted, ACD/Labs)0.44
  • No.of HBond Donors0
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA20.31
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA synthetic opioid analgesic, used mainly in Germany and Switzerland for treatment of moderate to severe pain, both acute and chronic.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability90.0
  • Protein bindingN/A
  • Volume of distribution (VD)19 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic demethylation
  • Half life4~6 h
  • ExcretionRenal, 90%
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A