• Molecular NameDiethylstilbestrol
  • SynonymDEB; DES; Diethylstilbesterol; Diethylstilbestrol BP; Diethylstilboesterol; Dietilestilbestrol; Percutatrine oestrogenique iscovesco; Rcra waste number U089; trans-Diethylstilbesterol; trans-Diethylstilbestrol; trans-Diethylstilboesterol
  • Weight268.356
  • Drugbank_IDDB00255
  • ACS_NO56-53-1
  • Show 2D model
  • LogP (experiment)5.07
  • LogP (predicted, AB/LogP v2.0)4.42
  • pkaN/A
  • LogD (pH=7, predicted)4.42
  • Solubility (experiment)0.012 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-4.88
  • LogSw (predicted, AB/LogsW2.0)0.02
  • Sw (mg/ml) (predicted, ACD/Labs)0.0
  • No.of HBond Donors2
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds4
  • TPSA40.46
  • StatusFDA approved
  • AdministrationIV, oral
  • PharmacologyA drug, an orally active synthetic nonsteroidal estrogen that was first synthesized in 1938. In 1971 it was found to be a teratogen when given to pregnant women.
  • Absorption_value90.0
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose include nausea and vomiting, and withdrawal bleeding may occur in females.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A