• Molecular NameAlbendazole
  • SynonymNA
  • Weight265.337
  • Drugbank_IDDB00518
  • ACS_NO54965-21-8
  • Show 2D model
  • LogP (experiment)3.299
  • LogP (predicted, AB/LogP v2.0)3.12
  • pkaN/A
  • LogD (pH=7, predicted)3.12
  • Solubility (experiment)Insoluble
  • LogS (predicted, ACD/Labs)(ph=7)-4.51
  • LogSw (predicted, AB/LogsW2.0)0.01
  • Sw (mg/ml) (predicted, ACD/Labs)0.01
  • No.of HBond Donors2
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds5
  • TPSA92.31
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.
  • Absorption_value5.0
  • Absorption (description)Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g)
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding70.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmOxidation of sulfur atom to sulfoxide, the active metabolite
  • Half life10 h
  • ExcretionN/A
  • Urinary Excretion<1
  • Clerance10~30.7 ml.min-1.kg-1
  • ToxicitySymptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A