• Molecular NameStreptozocin
  • SynonymNA
  • Weight265.222
  • Drugbank_IDDB00428
  • ACS_NO18883-66-4
  • Show 2D model
  • LogP (experiment)-1.45
  • LogP (predicted, AB/LogP v2.0)-1.46
  • pkaN/A
  • LogD (pH=7, predicted)-1.46
  • Solubility (experiment)5070 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-0.05
  • LogSw (predicted, AB/LogsW2.0)1309.21
  • Sw (mg/ml) (predicted, ACD/Labs)233.58
  • No.of HBond Donors5
  • No.of HBond Acceptors10
  • No.of Rotatable Bonds3
  • TPSA151.92
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 diabetes.
  • Absorption_value21.5
  • Absorption (description)Poor oral absorption (17-25%)
  • Caco_2N/A
  • Bioavailability21.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmPrimarily hepatic
  • Half life5~15 min
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose include nausea and vomiting, anorexia, myelosuppression; and nephrotoxicity.
  • LD50 (rat)N/A
  • LD50 (mouse)LD50=235 (ip)