• Molecular NameBufuralol
  • SynonymBufuralolum
  • Weight259.393
  • Drugbank_IDN/A
  • ACS_NO54340-62-4, 57704-15-1, 59652-29-8, 64100-61-4, 64100-62-5
  • Show 2D model
  • LogP (experiment)3.5
  • LogP (predicted, AB/LogP v2.0)3.07
  • pka9
  • LogD (pH=7, predicted)0.24
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.85
  • LogSw (predicted, AB/LogsW2.0)0.03
  • Sw (mg/ml) (predicted, ACD/Labs)0.14
  • No.of HBond Donors2
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds5
  • TPSA32.26
  • StatusDiscontinued
  • AdministrationN/A
  • PharmacologyAdrenergic beta-Antagonists
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability64.5
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityToxicity of the compound was determined after oral administration to mice in experiment, LD50=117
  • LD50 (rat)N/A
  • LD50 (mouse)N/A