- Molecular NameR-Albuterol
- SynonymNA
- Weight253.298
- Drugbank_IDN/A
- ACS_NO34391-04-3
- Show 3D model
- LogP (experiment)N/A
- LogP (predicted, AB/LogP v2.0)1.89
- pkaN/A
- LogD (pH=7, predicted)-0.62
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)-2.34
- LogSw (predicted, AB/LogsW2.0)18.22
- Sw (mg/ml) (predicted, ACD/Labs)1.16
- No.of HBond Donors4
- No.of HBond Acceptors5
- No.of Rotatable Bonds5
- TPSA89.79
- StatusN/A
- AdministrationN/A
- PharmacologyN/A
- Absorption_valueN/A
- Absorption (description)Systemic absorption is rapid following aerosol administration
- Caco_2N/A
- Bioavailability30.0
- Protein binding7.0
- Volume of distribution (VD)2.00 L/kg
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmHydrolyzed by esterases in tissue and blood to the active compound colterol. The drug is also conjugatively metabolized to albuterol 4'-O-sulfate.
- Half life1.6 h
- ExcretionN/A
- Urinary Excretion46
- Clerance10.3 ml.min-1.kg-1
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)LD50=1100 mg/kg