• Molecular NameGemfibrozil
  • SynonymNA
  • Weight250.338
  • Drugbank_IDDB01241
  • ACS_NO25812-30-0
  • Show 3D model
  • LogP (experiment)4.242
  • LogP (predicted, AB/LogP v2.0)3.93
  • pka4.8
  • LogD (pH=7, predicted)1.74
  • Solubility (experiment)10 mg/ml (in base)
  • LogS (predicted, ACD/Labs)(ph=7)-1.31
  • LogSw (predicted, AB/LogsW2.0)0.03
  • Sw (mg/ml) (predicted, ACD/Labs)0.09
  • No.of HBond Donors1
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds6
  • TPSA46.53
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyThe generic name for an oral drug used to lower lipid levels.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability98.0
  • Protein binding97.0
  • Volume of distribution (VD)0.14 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic (CYP3A4)
  • Half life1.1 h
  • ExcretionRenal 94% Feces 6%
  • Urinary Excretion<1
  • Clerance1.7 ml/min/kg
  • ToxicitySymptoms of overdose include abdominal cramps, diarrhea, joint and muscle pain, nausea, and vomiting.
  • LD50 (rat)N/A
  • LD50 (mouse)LD50 = 3162 mg/kg