• Molecular NameMethocarbamol
  • SynonymNA
  • Weight241.243
  • Drugbank_IDDB00423
  • ACS_NO532-03-6
  • Show 3D model
  • LogP (experiment)0.61
  • LogP (predicted, AB/LogP v2.0)0.52
  • pkaN/A
  • LogD (pH=7, predicted)0.52
  • Solubility (experiment)25 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.24
  • LogSw (predicted, AB/LogsW2.0)21.79
  • Sw (mg/ml) (predicted, ACD/Labs)13.75
  • No.of HBond Donors3
  • No.of HBond Acceptors6
  • No.of Rotatable Bonds7
  • TPSA91.01
  • StatusFDA approved
  • AdministrationOral, intravenous
  • PharmacologyA central muscle relaxant used to treat skeletal muscle spasms.
  • Absorption_value100.0
  • Absorption (description)Rapid. Onset of action is about 30 minutes after oral administration.
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding48.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life1~2 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySymptoms of overdose include blurred vision, coma, drowsiness, low blood pressure, nausea, and seizures.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A