• Molecular NameSecobarbital
  • Synonym(+/-)-Secobarbital; Secobarbital Sodium; Secobarbitale [DCIT]; Secobarbitalum [INN-Latin]; Sodium quinalbarbitone; Sodium Secobarbital
  • Weight238.287
  • Drugbank_IDDB00418
  • ACS_NO76-73-3
  • Show 3D model
  • LogP (experiment)1.97
  • LogP (predicted, AB/LogP v2.0)1.88
  • pka7.9
  • LogD (pH=7, predicted)1.83
  • Solubility (experiment)0.55 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-2.69
  • LogSw (predicted, AB/LogsW2.0)0.78
  • Sw (mg/ml) (predicted, ACD/Labs)0.43
  • No.of HBond Donors2
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds5
  • TPSA75.27
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA barbiturate derivative drug that was first synthesized in 1928. It possesses anaesthetic, anticonvulsant, sedative and hypnotic properties.
  • Absorption_value90.0
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding26.0
  • Volume of distribution (VD)1.5 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half lifePlasma half-life, 19 to 34 h (mean 28).
  • ExcretionRenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A