• Molecular NamePractolol
  • SynonymTocris-0831
  • Weight236.315
  • Drugbank_IDDB01297
  • ACS_NO6673-35-4
  • Show 3D model
  • LogP (experiment)0.74
  • LogP (predicted, AB/LogP v2.0)0.81
  • pka9.5
  • LogD (pH=7, predicted)-1.67
  • Solubility (experiment)2.5 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)0.63
  • LogSw (predicted, AB/LogsW2.0)51.74
  • Sw (mg/ml) (predicted, ACD/Labs)25.64
  • No.of HBond Donors3
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds5
  • TPSA61.36
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA selective beta blocker that has been used in the emergency treatment of cardiac arrhythmias.
  • Absorption_value95.0
  • Absorption (description)N/A
  • Caco_2-6.05
  • Bioavailability95.0
  • Protein binding10.0
  • Volume of distribution (VD)1.6 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life10~13 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A