• Molecular NameDiloxanide
  • SynonymDiloxanide furoate
  • Weight234.082
  • Drugbank_IDN/A
  • ACS_NO3736-81-0
  • Show 3D model
  • LogP (experiment)1.78
  • LogP (predicted, AB/LogP v2.0)1.66
  • pkaN/A
  • LogD (pH=7, predicted)1.66
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-1.69
  • LogSw (predicted, AB/LogsW2.0)1.55
  • Sw (mg/ml) (predicted, ACD/Labs)4.82
  • No.of HBond Donors1
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds2
  • TPSA40.54
  • StatusN/A
  • AdministrationN/A
  • PharmacologyAn anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections.
  • Absorption_value90.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability90.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHydrolyzed to furoic acid and diloxanide, which undergoes extensive glucuronidation
  • Half life3 h
  • ExcretionRenal (90%), fecal (10%)
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A