• Molecular NameNicorandil
  • SynonymNA
  • Weight211.177
  • Drugbank_IDN/A
  • ACS_NO65141-46-0
  • Show 2D model
  • LogP (experiment)0.43
  • LogP (predicted, AB/LogP v2.0)0.61
  • pkaN/A
  • LogD (pH=7, predicted)0.61
  • Solubility (experiment)15 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.1
  • LogSw (predicted, AB/LogsW2.0)28.56
  • Sw (mg/ml) (predicted, ACD/Labs)16.59
  • No.of HBond Donors1
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds5
  • TPSA100.05
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA vasodilatory drug used to treat angina.
  • Absorption_value100.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability75.0
  • Protein binding25.0
  • Volume of distribution (VD)1.0 to 1.4 L/kg; also reported as 100 L.
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life1 h
  • ExcretionRenal (21%)
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A