• Molecular NameProflavine
  • SynonymNA
  • Weight209.252
  • Drugbank_IDDB01123
  • ACS_NO92-62-6
  • Show 3D model
  • LogP (experiment)1.83
  • LogP (predicted, AB/LogP v2.0)1.96
  • pka8.1
  • LogD (pH=7, predicted)-0.72
  • Solubility (experiment)500 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.47
  • LogSw (predicted, AB/LogsW2.0)0.02
  • Sw (mg/ml) (predicted, ACD/Labs)0.06
  • No.of HBond Donors4
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds0
  • TPSA64.93
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyAn acriflavine derivative, a disinfectant bacteriostatic against many gram-positive bacteria. It has been used in the form of the dihydrochloride and hemisulfate salts as a topical antiseptic, and was formerly used as a urinary antiseptic.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)LD50>1000 (peroral)