- Molecular NameProflavine
- SynonymNA
- Weight209.252
- Drugbank_IDDB01123
- ACS_NO92-62-6
- Show 3D model
- LogP (experiment)1.83
- LogP (predicted, AB/LogP v2.0)1.96
- pka8.1
- LogD (pH=7, predicted)-0.72
- Solubility (experiment)500 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)-1.47
- LogSw (predicted, AB/LogsW2.0)0.02
- Sw (mg/ml) (predicted, ACD/Labs)0.06
- No.of HBond Donors4
- No.of HBond Acceptors3
- No.of Rotatable Bonds0
- TPSA64.93
- StatusFDA approved
- AdministrationN/A
- PharmacologyAn acriflavine derivative, a disinfectant bacteriostatic against many gram-positive bacteria. It has been used in the form of the dihydrochloride and hemisulfate salts as a topical antiseptic, and was formerly used as a urinary antiseptic.
- Absorption_valueN/A
- Absorption (description)N/A
- Caco_2N/A
- BioavailabilityN/A
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmN/A
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)LD50>1000 (peroral)